Microsoft 365 includes the robust Office desktop apps that you’re familiar with, like Word, PowerPoint, and Excel. Microsoft 365 is a subscription that includes the most collaborative, up-to-date features in one seamless, integrated experience. However, there are no upgrade options which means if you plan to upgrade to the next major release, you'll have to buy it at full price. One-time purchases are available for both PCs and Macs.
Office 2019 is sold as a one-time purchase, which means you pay a single, up-front cost to get Office apps for one computer.